Diflucan (fluconazole) is a highly-efficient antifungal medication used to treat infections that affected the blood, genital area, mouth, lungs, esophagus, bladder, and throat. The following health conditions must be reported to your health care provider: liver or kidney disease, a history of Long QT syndrome or a heart rhythm disorder. These are likely to interfere with your treatment so your dose may need to be adjusted. Continue taking Diflucan for the entire period prescribed by your doctor, as otherwise your infection will not be treated completely. Report any of the health conditions you have to your doctor before asking him for a prescription.